Adeno-associated viral vectors (AAVs) are a type of vector that is used to transfer genes into cells. AAVs work by entering the cell through the cell membrane and then traveling to the nucleus, where they use “recombinant DNA” (rDNA) to insert the gene of interest.
Unlike other vectors, such as viruses and bacteria, AAVs do not require a host to reproduce. This makes them an ideal choice for gene therapies and other medical applications. You can also pop over to this site to get more information about AAV.
For gene therapies, AAVs are injected into the patient’s bloodstream. Once in the body, they travel to the appropriate cells and start replicating. This process injects copies of the AAV into the cell, which can then be used to deliver the gene of interest.
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In some cases, this process can be done using “non-viral delivery methods” such as liposomes or electroporation. However, when using this type of delivery method there is a higher risk that the gene will not be delivered properly or at all.
For medical applications such as organ transplants or cancer treatment, it is important that the gene is delivered as efficiently as possible.
The Adeno-associated viral vector (AAV) is a delivery vehicle that has shown promise in treating a variety of diseases, including various cancers. AAV is unique in that it can integrate into the host cell's genome and be activated only when needed, which makes it an ideal treatment for conditions where traditional therapies are ineffective or not tolerated.